Jan. 23, 2003. Jonathan C. Makielski, MD, Professor, Medicine (Cardiovascular).

Variant of SCN5A Sodium Channel Implicated in Risk of Cardiac Arrhythmia, Igor Splawski, Katherine W. Timothy, Michihiro Tateyama, Colleen E. Clancy, Alka Malhotra, Alan H. Beggs, Francesco P. Cappuccio, Giuseppe A. Sagnella, Robert S. Kass, Mark T. Keating, Science, Vol 297, Aug 23, 2002, pp 1333-1336.

Feb. 27, 2003 Hector Valdivia, MD, Ph.D. Associate Professor, Physiology.

Vinogradova TM, Bogdanov KY, Lakatta EG. (2002) beta-Adrenergic stimulation modulates ryanodine receptor Ca(2+) release during diastolic depolarization. to accelerate pacemaker activity in rabbit sinoatrial nodal cells. Circ Res 90(1):73-9

Yang HT, Tweedie D, Wang S, Guia A, Vinogradova T, Bogdanov K, Allen PD, Stern MD, Lakatta EG, Boheler KR. (2002) The ryanodine receptor modulates the spontaneous beating rate of cardiomyocytes during development. Proc Natl Acad Sci USA 99(14):9225-30

Mar. 27, 2003. Blake Anson, Ph.D. Assistant Scientist, Medicine (Cardiovascular)

A novel mutation (T65P) in the PAS domain of the human potassium channel HERG results in the long QT syndrome by trafficking deficiency. Paulussen A, Raes A, Matthijs G, Snyders DJ, Cohen N, Aerssens J. J Biol Chem 2002 Dec 13;277(50)48610-6

Apr. 24, 2003. Lee L. Eckhardt, MD Postdoctoral Trainee.

KCNJ2 Mutation Results in Andersen Syndrome with Sex-Specific Cardiac and Skeletal Muscle Phenotypes, Gregor Andelfinger, Andrew R. Tapper, Richard C. Welch, Carlos G. Vanoye, Alfred L. George Jr., and D. Woodrow Benson, Am. J. Hum. Genet. 71:663668, 2002

Novel KCNJ2 Mutation in Familial Periodic Paralysis With Ventricular Dysrhythmia, Tomohiko Ai, MD, PhD; Yuichiro Fujiwara, MD; Keiko Tsuji, BSc; Hideo Otani, MD; Shozo Nakano, MD, PhD; Yoshihiro Kubo, MD, PhD; Minoru Horie, MD, Ph.D. Circulation, 2002; 105: 2592-2594

May 22, 2003. Roberto Coronado, Ph.D., Professor, Physiology.

Cancelled - rescheduled for Fall semester