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Ion Channels/Arrhythmia Journal Club Schedule (2006-2007)
Fourth Thursdays, 11 AM - 12:30 PM
Room 116 Service Memorial Institute
1300 University Avenue
Jonathan C. Makielski, MD, Professor, Medicine (Cardiovascular), Chair
Contact info@cvrc.wisc.edu for further information
Fall 2006
Sep. 28, 2006
Amanda Farley, Graduate Student, Physiology and Trainee, Training Program in Translational Cardiovascular Science
Arrhythmogenesis in Catecholaminergic Polymorphic Ventricular Tachycardia: Insights From a RyR2 R4496C Knock-In Mouse Model Nian Liu, Barbara Colombi, Mirella Memmi, Spyros Zissimopoulos, Nicoletta Rizzi, Sara Negri, Marcello Imbriani, Carlo Napolitano, F. Anthony Lai and Silvia G. Priori, Circulation Research 2006: 99; 292-298.
Abnormal Interactions of Calsequestrin With the Ryanodine Receptor Calcium Release Channel Complex Linked to Exercise-Induced Sudden Cardiac Death Dmitry Terentyev, Alessandra Nori, Massimo Santoro, Serge Viatchenko-Karpinski, Zuzana Kubalova, Inna Gyorke, Radmila Terentyeva, Srikanth Vedamoorthyrao, Nico A. Blom, Giorgia Valle,Carlo Napolitano, Simon C. Williams, Pompeo Volpe, Silvia G. Priori, Sandor Gyorke, Circulation Research 2006;98:1151-1158.
Recommended Review article: Catecholaminergic polymorphic ventricular tachycardia: Recent mechanistic insights Kimmo Kontula,T, PaĻivi J. Laitinen, Annukka Lehtonen, Lauri Toivonen, Matti Viitasalo, Heikki Swan Cardiovascular Research 67 (2005) 379 387.
Oct. 26, 2006
Beth Altschafl, Ph.D., Postdoc, Physiology and former Trainee, Training Program in Translational Cardiovascular Science
Excitation-Contraction Coupling in Na+-Ca2+ Exchanger Knockout Mice: Reduced Transsarcolemmal Ca2+ Flux Christian Pott, Kenneth D. Philipson, and Joshua I. Goldhaber, Circ. Res. 2005;97:1288-1295
Mechanism of Shortened Action Potential Duration in Na+-Ca2+ Exchanger Knockout Mice Christian Pott, Xiaoyan Ren, Diana X. Tran, Ming-Jim Yang, Scott Henderson, Maria C. Jordan, Kenneth P. Roos, Alan Garfinkel, Kenneth D. Philipson, and Joshua I. Goldhaber, Am J Cell Physiol. August 30, 2006; 1-33
Nov. 16, 2006 (one week early due to holiday)
Jason Foell, Graduate Student, Physiology and Trainee, Training Program in Translational Cardiovascular Science
B-Adrenergic Stimulation of L-type Ca2+ Channels in Cardiac Myocytes Requires the Distal Carboxyl
Terminus of A1C but Not Serine 1928 Anand N. Ganesan, Christoph Maack, David C. Johns, Agnieszka Sidor, Brian O'Rourke
Circ Res. 2006; 98:e11-e18.
Phosphorylation of serine 1928 in the distal C-terminal domain of cardiac CaV1.2 channels during b1-adrenergic regulation Joanne T. Hulme, Ruth E. Westenbroek, Todd Scheuer, and William A. Catterall PNAS 2006;103;16574-16579; originally published online Oct 19, 2006.
Dec. 21, 2006 (one week early due to Christmas holiday)
Eugenia Jones, Ph.D.,
Associate Scientist,
Physiology
Molecular Coupling of a Ca2+-Activated K+ Channel to L-type Ca2+ Channels via a-Actinin2 Ling Lu, Qian Zhang, Valeriy Timofeyev, Zhao Zhang, J. Nilas Young, Hee-Sup Shin, Anne A. Knowlton, Nipavan Chiamvimonvat, Circulation Research, Proof copy, Original received May 19, 2006; resubmission received September 13, 2006; revised resubmission received November 06, 2006; accepted November 8, 2006.
Spring 2007
Jan. 25, 2007
Brian P. Delisle, Ph.D.,
Assistant Scientist,
Medicine (Cardiovascular)
HERG is Protected from Pharmacological Blockade by Constitutive a-1,2-Glucosyltransferase Function
Tadashi Nakajima, Kenshi Hayashi, Prakash C. Viswanathan, Min-Young Kim, Mircea Anghelescu, Kate A. Barksdale, Wen Shuai, Jeffrey R. Balser, Sabina Kupershmidt. JBC Papers in Press. Published on December 21, 2006 as Manuscript M605976200.
Feb. 22, 2007
Baron Chanda, Ph.D., Assistant Professor, Physiology
Enzymatic activation of voltage-gated potassium channels
Yajamana Ramu, Yanping Xu and Zhe Lu. Nature (Aug 2006) 442/10:696-699.
Mar. 22, 2007
Eric Lin, Graduate Student, Physiology
Gating currents associated with intramembrane charge displacement in HERG potassium David R. Piper, Anthony Varghese, Michael C. Sanguinetti, and Martin Tristani-Firouzi PNAS 2003;100;10534-10539; originally published online Aug 19, 2003
Apr. 26, 2007
Rebecca Uelmen, Graduate Student, Physiology
Regulation of Endocytic Recycling of KCNQ1/KCNE1 Potassium Channels
Guiscard Seebohm, Nathalie Strutz-Seebohm, Ria Birkin, Ghislaine Dell, Cecilia Bucci, Maria R. Spinosa,
Ravshan Baltaev, Andreas F. Mack, Ganna Korniychuk, Amit Choudhury, David Marks, Richard E. Pagano,
Bernard Attali, Arne Pfeufer, Robert S. Kass, Michael C. Sanguinetti, Jeremy M. Tavare, Florian Lang Circ Res. 2007;100:686-692.
May 24, 2007
Jabe Best, Graduate Student, Molecular and Cellular Pharmacology
cAMP microdomains and L-type Ca2+ channel regulation in guinea-pig ventricular myocytes,
Warrier S, Ramamurthy G, Eckert RL, Nikolaev VO, Lohse MJ, Harvey RD J Physiol. 2007 May 1;580(Pt.3):765-76. Epub 2007 Feb 8.
Click here for the 2005-2006 schedule
Click here for the 2004-2005 schedule
Click here for the 2003-2004 schedule
Click here for the 2002-2003 schedule
Click here for the 2001-2002 schedule
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