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Research Area: Ischemic Heart Disease
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The heart is a muscular pump which requires an adequate supply of oxygen and nutrients to function normally. These needs are met by blood flow through the coronary arteries. Blood flow to the heart varies to meet the demands of the heart at rest and during exercise or stress.
Myocardial ischemia occurs when there is inadequate blood flow to the heart. In people, myocardial ischemia can result in a variety of symptoms and consequences, ranging from angina pectoris to myocardial infarction (heart attack) and sudden death.
Research in the UW Cardiovascular Research Center covers a broad spectrum of myocardial ischemia and ischemic heart disease. There is ongoing basic research using animal and heart cell models to better understand the metabolic, electrical, and functional consequences of ischemia. The goal of this work is to increase our understanding of ischemia so improved preventive and treatment strategies can be developed.
There is also a wide variety of clinical research protocols that include new medications to treat angina, clot preventing and clot dissolving agents, and cardiac catheterization based approaches for opening blocked arteries to relieve ischemia.
UW Cardiovascular Research Center members involved in ischemic heart disease research include:
| Name | Title | Department | | Leonelo E. Bautista, MD, Ph.D., M.P.H. | Assistant Professor | Population Health Sciences | | Daryl D. Buss, DVM, Ph.D. | Dean and Professor | Veterinary Medicine | | Thomas M. Grist, MD | Professor and Chair | Radiology | | Timothy A. Hacker, Ph.D. | Assistant Scientist | Medicine (Cardiovascular) | | Robert A. Haworth, Ph.D. | Distinguished Scientist | Surgery | | Kurt W. Saupe, Ph.D. | Assistant Professor | Medicine (Cardiovascular) | | Charles K. Stone, MD | Associate Professor | Medicine (Cardiovascular) | | Matthew R. Wolff, MD | Associate Professor | Medicine (Cardiovascular) |
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